Search on: COILED-COIL KINASE, RHO-ASSOCIATED 
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Descriptor English:   rho-Associated Kinases 
Descriptor Spanish:   Quinasas Asociadas a rho 
Descriptor Portuguese:   Quinases Associadas a rho 
Synonyms English:   ROCK Protein Kinases
ROCK-I Protein Kinase
ROCK-II Protein Kinase
ROK Kinase
p160 rhoA-Binding Kinase ROKalpha
p160ROCK
rho-Associated Coiled-Coil Containing Protein Kinase 1
rho-Associated Coiled-Coil Containing Protein Kinase 2
rho-Associated Coiled-Coil Kinase
rho-Associated Kinase 1
rho-Associated Kinase 2
rho-Associated Kinase alpha
rho-Associated Kinase beta
rho-Associated Protein Kinase alpha
rho-Associated Protein Kinase beta
rho-Kinase
Coiled-Coil Kinase, rho-Associated
Protein Kinases, ROCK
ROCK I Protein Kinase
ROCK II Protein Kinase
p160 rhoA Binding Kinase ROKalpha
rho Associated Coiled Coil Containing Protein Kinase 1
rho Associated Coiled Coil Containing Protein Kinase 2
rho Associated Coiled Coil Kinase
rho Associated Kinase
rho Associated Kinase 1
rho Associated Kinase 2
rho Associated Kinase alpha
rho Associated Kinase beta
rho Associated Kinases
rho Associated Protein Kinase alpha
rho Associated Protein Kinase beta
rho Kinase
rho-Associated Kinase  
Tree Number:   D08.811.913.696.620.682.700.814
D12.644.360.590
D12.776.476.595
Definition English:   A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES. 
History Note English:   2008 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   52746 
Unique Identifier:   D054460 

Occurrence in VHL:
 

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